Systematic Models for Biological Systems Engineering Training Network
The training programme and approach pursued by the SyMBioSys consortium has been designed to address the following main concerns:
- train young researchers with cross-disciplinary skills encompassing biological experimentation, mathematical modeling and optimization, as well as software engineering, to enhance understanding of biological processes;
- achieve real understanding and adequate communication between the different research communities involved (systems and software engineers, modelers and biologists). The aim is to reinforce the coherence in biological systems engineering field, ending up with complementarities and future activities;
- strengthen the academic-industrial links in biological systems engineering area. The SyMBioSys approach is promising to enormously benefit White and Red Biotech companies by providing applications that help anticipate project failure at an early stage and shorten product development timeframes;
- provide a platform for young researchers to enhance their network, knowledge and career opportunities. SyMBioSys will address these concerns through the training of 15 ESRs, who will be moving between the academic and industrial sectors, within the dynamic environment of 5 universities, 2 research centres and 4 companies. The ESRs will aim at solving cross-disciplinary problems supervised by researchers of different backgrounds.
ESR N. |
Project Title |
Full name |
ESR1 |
Unraveling the main control structure of the yeast core carbon metabolism |
Joana Saldida Alves |
ESR2 |
Capturing Heterogeneity across many scales in Biosystems using Population Balance Modelling |
Romuald Győrgy |
ESR3 |
Modeling of cell signaling via hybrid networks |
Aurelien Dugourd |
ESR4 |
Metabolism in mathematical modelling and bioprocess development for mesenchymal stem cell osteogenic differentiation in 2D and 3D cultures |
Michail Klontzas |
ESR5 |
Identification of logic-based dynamic models of biochemical networks |
Enio Gjerga |
ESR6 |
Systematic reverse-engineering methods for dynamic model identification, selection and discrimination |
Jake Pitt |
ESR7 |
Optimal control methods to explain and predict operating principles in biochemical pathways |
Nikolaos Tsiantis |
ESR8 |
Optimal metabolic regulation through cell signaling |
Roman Rainer |
ESR9 |
Drug target detection as optimality problem |
Olufemi Ademola Bolaji |
ESR10 |
Algorithms and software tools for calibration of biological process models |
Lucian Gomoescu |
ESR11 |
Application of the new algorithms and software tools to biological test cases, from the analysis of metabolic and signaling networks to metabolic engineering and biomedical problems |
Sara Barbosa |
ESR12 |
Development of bi-level strain optimization algorithms and software tools |
Osvaldo Kim |
ESR13 |
Model-based optimization for personalized leukemia treatment using an integrated experimental / computational platform |
Jose Ferreira Rodrigues De Morais |
ESR14 |
Integration of signaling models with clinical databases and proteomic, phopshoproteomic, transcriptomic, and genomic data |
Asier Antoranz |
ESR15 |
Large-scale kinetic model of human metabolism |
Maria Masid Barcon |